MHRA Information and safety alerts

The Central Alerting System (CAS) is a web-based cascading system for issuing patient safety alerts, important public health messages and other safety critical information and guidance to the NHS and others, including independent providers of health and social care.

Alerts available on the CAS website include safety alerts, CMO messages, drug alerts, Dear Doctor letters and Medical Device Alerts.

You can also sign up to receive Email alerts directly from the MHRA (Medicines and Healthcare Products Regulatory Agency):

by visiting

Drug alerts and medical device alerts

Subscribe to MHRA’s alerts and recalls for drugs and medical devices.

Drug Safety Update

Subscribe to the Drug Safety Update, the monthly newsletter for healthcare professionals, with clinical advice on the safe use of medicines.

News and publications from the MHRA

Subscribe to MHRA’s new publications, statistics, consultations and announcements.